only a question mark appears, it does not show the citizens or the monsters

Hi, For some reason the game won't let me chose a highter resolution than 1024x768. I do not have this issue with any other game. Has anyone else had this problem? Any solutions?

I have all 10 brats in my inventory but cannot complete the mission as the game only registers me having 3/10. Really annoying since I'm trying to get the last achievement.

I beat the boss in the last forest mission but the mission didn't count as finished and i couldn't any other missions. After that i restarted the game and it spawned me in front of the doctor npc that I should talk to except for the fact that she's not there, literally....

I loaded the game and my entire progress with power up, collectibles reset to zero. I almost completed the game and I'm totally block with rest of achievments - it's force me to play a new game. Also game saves to the registry, I don't have any save backups what to do?...