only a question mark appears, it does not show the citizens or the monsters

Hi, For some reason the game won't let me chose a highter resolution than 1024x768. I do not have this issue with any other game. Has anyone else had this problem? Any solutions?

I did almost 100% of the game, the only thing I couldn't do was this achievement, there was some bug where the civilians who need help don't appear, the mission is on the mini map but no enemies appear, I've tried respawn, restarting the game, fast travel and it never works again, does anyone have a tip to solve it?...

I have all 10 brats in my inventory but cannot complete the mission as the game only registers me having 3/10. Really annoying since I'm trying to get the last achievement.

I loaded the game and my entire progress with power up, collectibles reset to zero. I almost completed the game and I'm totally block with rest of achievments - it's force me to play a new game. Also game saves to the registry, I don't have any save backups what to do?...