There was already an guide for this in the Original game, so maybe it could help you more than this one?

https://steamproxy.net/sharedfiles/filedetails/?id=475142385

- You can go to your game's folder(You can access through Properties --> Local Files --> Browse Local Files), then go towards Binaries/Win64 and start BorderlandsGOTY.exe as admin.

- You can create a firewall exception, or even create a manual rule for BorderlandsGOTY.exe. For a more in depth guide on this....google.


-From the Guide above, and an answer from 2K's support:

1. Go to the following folder: \Program Files\Steam\steamapps\common\Borderlands\Binaries\
2. Once there, you would need to make a copy of the file called cudart.dll and rename this copy to physxcudart_20.dll

Disclaimer: If you end up doing this method, and...it works, this either means that:
1. You are using a integrated GPU instead of your dedicated.
2. Your GPU does not support DX11

So do this at your own risk, because you will get some...very interesting things once you do this.
https://steamproxy.net/sharedfiles/filedetails/?id=1704416958

- Get dxcpl. You MAY probably already have it, you can try searching for it(if you are using Windows 10), but if you don't, you can download it here[www.microsoft.com].

- Once you get dxcpl and start it, you'll be greeted with an unfamiliar window[i.imgur.com]. Once you get your bearings, go to Edit List... and add BorderlandsGOTY.exe to it.

-Go back to the previous window, and set Feature level limit to 11_0, and make sure Force WARP is ticked.

-Start the game, and be greeted by glorious 3 FPS!

Yeah, if you probably were wishing to play this remaster, due to its improvements, think again, because they upgraded the game soo much that people who could previously run the game perfectly and flawlessly in 60 FPS can barely run it or even start it anymore.

I'm sorry for that, please discuss that with the developers who made the remaster.