Getting 100% was frustrating even with a guide due to technical issues.

approximate amount of time to 100%: 10-20h
Estimated achievement difficulty: 1/10 With guide, 3-4 without.
Minimum number of playthroughs needed: 1
Multiplayer achievements: No Multiplayer.
Missable achievements: Yes. about 5 or 6, See guides.
Grinding Achievements: No.
DLC-Only achievements: No.
Time-gated achievements: No.
Speed-run achievements: No.
RNG-achievements: No.
Does difficulty affect achievements: No choice.
Unobtainable/glitched achievements: Yes. some users complain about "Best buddies" and "Game Complete" not unlocking. WTF for that last one.
First achievement unlock: "Completed tutorial" or if you skip that "Found evidence of Sabotage" on the first map.
Point of no return: No,
Is there a good guide: F.o.B's 100% Guide steam is good for getting the achievements in order. There's other guides for solutions if you get stuck, such as jackanape's on XboxAchievement forums.

Notes:

The game crashes for me on scene change every 10-15 minutes. Sometimes the auto-save is 1 minute ago, sometimes it's 10 minutes ago. :|
The game is infuriatingly slow (probably to pad the run-time) The characters wait for the drawn-out animations to trigger the next voice line. Who the hell coded this?
I'd complain about the moon-logic, but i'm guessing that part doesn't actually anger the fans. Without spoiling, I will note the "connect the high voltage nodes" somewhere high up, towards the end to be one of the worst examples, you'll know it when you see it.
Add another "Best watch someone else play it than suffer it yourself" game to the pile.

Overall, not recommended, not for this price, not even in the humble bundle from ages ago. Sorry, It's just not worth it.

Getting 100% was frustrating even with a guide due to technical issues. approximate amount of time to 100%: 10-20h Estimated achievement difficulty: 1/10 With guide, 3-4 without. Minimum number of playthroughs needed: 1 Multiplayer achievements: No Multiplayer. Missable achievements: Yes. about 5 or 6, See guides. Grinding Achievements: No. DLC-Only achievements: No. Time-gated achievements: No. Speed-run achievements: No. RNG-achievements: No. Does difficulty affect achievements: No choice. Unobtainable/glitched achievements: Yes. some users complain about "Best buddies" and "Game Complete" not unlocking. WTF for that last one. First achievement unlock: "Completed tutorial" or if you skip that "Found evidence of Sabotage" on the first map. Point of no return: No, Is there a good guide: F.o.B's 100% Guide steam is good for getting the achievements in order. There's other guides for solutions if you get stuck, such as jackanape's on XboxAchievement forums. Notes: The game crashes for me on scene change every 10-15 minutes. Sometimes the auto-save is 1 minute ago, sometimes it's 10 minutes ago. :| The game is infuriatingly slow (probably to pad the run-time) The characters wait for the drawn-out animations to trigger the next voice line. Who the hell coded this? I'd complain about the moon-logic, but i'm guessing that part doesn't actually anger the fans. Without spoiling, I will note the "connect the high voltage nodes" somewhere high up, towards the end to be one of the worst examples, you'll know it when you see it. Add another "Best watch someone else play it than suffer it yourself" game to the pile. Overall, not recommended, not for this price, not even in the humble bundle from ages ago. Sorry, It's just not worth it.