The Iga Clan is an ancient ninja dog clan led by Akame. They're very skilled, and have lots of different techniques. They are known for their good leap power, and can jump in trees with ease.

In Ginga: Nagareboshi Gin, the Iga Clan is in the midst of an intense feud with the Kōga Clan led by Kurojaki, who is also the father of Tesshin. When Ben's platoon arrives in Iga territory, the Kōga dogs trick the Igas into thinking that Ben and the others are Kōgas. This causes the Igas to attack Ben's platoon where they kidnap Smith and lure the others to their base where they are poisoned by Akame. Akame soon realizes that he accidentally hurt the wrong pack of dogs. Despite that, Akame and the other Igas cure them, even though Ben is left with damaged eyesight. After the battle with the Kōga Clan, Akame and several other Igas accompany Ben and the others and the rest of the Iga Clan are not seen again.