Note: This guide was from my April 2022 Review for the game. With more than 190 users found it helpful.
Source: https://steamproxy.net/id/AzaiKang/recommended/631510?snr=1_5_9__402

Anyways....
What I hate about the HD Collection is that your save files will not work after uninstalling and then reinstalling. To properly load your save file. This method works for the 3 games. Be careful on what you backup!

1. Make sure you create a BACKUP of your save files before uninstalling. Your saves are located at Steam\userdata\*YOUR STEAM ID*\631510\remote
2. When you feel like playing DMC again after reinstalling, Play any DMC game.
3. You'll notice your saved progresses are gone! create a new save state within the game. (I recommend to play each DMC games if you have played it all, create a save file for each game and you're good to go)
4. Quit the game.
5. Go to your folder and then paste the backup saves to its original directory.
6. Open the game and then enjoy.
7. If you want to UNINSTALL the game. Repeat STEP 1. This game doesn't support Steam Cloud.