1st
Set in game settings to optimal 50-80 fps
where You like how the game looks like.

set native resolution to your screen
set fullscreen windowed
Framerate: Unlimited

"My" in game settings
Yours could be different, just set up your settings to get 50-70 fps
then follow to next step of this guide :
















































2nd.

- add Borderlands 2 in Windows Settings - Graphics settings - performance preference:
set to High Performance

- set in Nvidia control panel or /AMD settings:

I'm recommending: switch off: G-sync or Free sync off
set monitor technology to fixed refresh rate and set max fps to match your monitor refresh rate
and ofcourse set maximum performance ect:

My Nvidia Control Panel:









































3rd
Change settings in engine and world .ini files

go to: C:\Users\username\Documents\My Games\Borderlands 2\WillowGame\Config

- Open WillowGame.ini. change values as bellow, save and set as read only.

Disable software PhysX:
Add the following to the end of the file:

bPhysXEnabled=False

Shorter body decay
Find the following lines and set them to these values:

SecondsBeforeConsideringRagdollRemoval=5.0
SecondsBeforeVisibleRagdollRemoval=15.0
SecondsBetweenRagdollRemovalAttempts=1.0
SecondsBeforePhysicsShutsDown=8.0

* save and set as read only

- Open WillowEngine.ini change as bellow, save and set as read only.

Disable software PhysX:
Under [Engine.Engine] add this line:
bDisablePhysXHardwareSupport=True

Disable dynamic shadows:
Find the following line and set it
DynamicShadows=False

Change these lines according to Your GPU video memory size:
[MemoryBudgets]
AnimationMB=5000
AudioMB=5000
CodeMB=5000
LevelObjectsMB=5000
TerrainMB=5000
GameDataMB=5000
MaterialMB=5000
ParticleMB=5000
PhysicsMB=5000
ScaleformMB=5000
ShadersMB=5000
SkelMeshMB=5000
StaticMeshMB=5000
TextureMB=4000
Reduced particles:
Find the following line and set it 512.
MaxParticleResize=512

Find the [SystemSettings] section and change to:
OnlyStreamInTextures=True

* save and set as read only

- Open WillowInput.ini.
Enable the console ctrl + ~ or ctrl + \
Find the [Engine.Console] section and change these values:
ConsoleKey=Tilde
TypeKey=Backslash