Grab Speedster (or Chonko or Ranger if you don't like purple boi) with speed, hp, damage, cooldown and pierce as your modules, all pretty important here

DO NOT pick Explosives or Splitshot. You want to get as much damage as possible before infinity phase, i recommend (in 1.1) Overclock, Torpedo, Multishot and Infliction. If you see one of these for the first time, grab it even if you want something else more (having picked a card at least once increases it's chance to roll again)

Avoid fluff (anything that isn't damage) except XP Gain and Stun. Eagle Eye might help (and picking it declutters the pool), and Teleport can completely undo misplays and be used as a reroll if you pick another secondary while you have it. DO NOT upgrade teleport as this stops you from using it to reroll and is a waste, besides

This map is a race against time to grab enough damage before Hammerheads (the only enemy which drops crystals in infinity phase) become too tanky to kill before they leave the map, locking you out of getting any synergies

Splitshot and Explosives both increase your knockback, which is no help with killing Hammerheads. Stun does help, and can also give you more time to maneuver around the Gyro (big spinny purple thing), as can Teleport

Keeping Teleport at level 1 allows you to use it to cycle secondary cards for free for extra rerolls, this doesn't matter as much after you have most of the damage upgrades you'll get (don't forget Powershots and crit, these are worse than the stuff on the TL;DR, but far more important than upgrading a secondary), at which point it's a tossup between keeping Teleport and going for Earthquake

As tempting as being still might be, moving is better. do (square) laps around the map (unless you need to dodge Gyro) when you have enough damage to clear a path. If you went Speedster (and thus have enough firerate to cover a wider area) you can sway your aim to keep a larger swath clear of enemies (careful not to swing too fast and let stuff through, this probably isn't worth the effort unless you're going for a time record)

This was used to get to 46:25 on 1.1, with admittedly very broken torpedoes, but should still work (if less fantastically) if/when they're nerfed (i remember doing a 20 minute run before the Torpedo hype)

I'm sure this is doable in a variety of ways, this is how I did it

Many thanks to Wind is Here from the game's Discord[discord.com] (windrhider on Steam) for the tierlist template, and to the Dev for this shiny, shiny game

I might do a bigger (and actually formatted) guide for the game in general if there's any demand for it and/or I'm bored, so there's that

I'm making a full guide on everything i can think of, but it is currently very incomplete. Turns out i was indeed bored.

Farewell, travelers.

Done in 1.1: