To find your RE4 folder go to \Documents\My Games\Capcom\RE4\.

There you will find two files. Config.ini and usr_input.ini

Open Config.ini in Notepad, and at the bottom you'll see a variety of values.

laserR 255
laserG 0
laserB 0
laserA -1

These are all RGB values. LaserR refers to the color Red, LaserG refers to the color Green, and LaserB refers to the color Blue. Laser A refers to the transparency, or how bright the laser is. By default, red is set to 255 and transparency to -1. Note: These variables will not be present in the config.ini file before the 1.0.6 patch. In order to make them appear, simply edit graphic settings, return to main menu, and close the game. Or alternatively add the variables to the .ini yourself.

Note that setting the transparency to -1 will always set it to red. If you wish to change the color, you must also change the transparency.

You may edit these values however you want, remember to save after editing. These settings also apply for all other playable characters (IE: Ada, HUNK, Wesker, etc) and all of the player's weapons. For a list of RGB values for colors, there's a handy site right here.

http://cloford.com/resources/colours/500col.htm

laserR 0
laserG 255
laserB 0
laserA 255


laserR 255
laserG 0
laserB 0
laserA -1


laserR 0
laserG 0
laserB 255
laserA 255


laserR 0
laserG 238
laserB 238
laserA 255


laserR 255
laserG 255
laserB 0
laserA 255


laserR 255
laserG 100
laserB 0
laserA 255


laserR 255
laserG 255
laserB 255
laserA 255


laserR 255
laserG 130
laserB 170
laserA 255


laserR 155
laserG 48
laserB 255
laserA 255

To remove Leon's lasersight you can change all the colors to 0

laserR 0
laserG 0
laserB 0
laserA 255