tl;dr - An incomplete complete Zoe guide. I'll keep adding to this but I was home sick today and decided to nerd it out with the DLC.

Putting a partial guide up for what I've found out playing the DLC material so far. Decided to focus in on our favorite little eldritch cutie. Really enjoying the new material she brings to the core characters. Definitely best kawaii waifu.

Sorry for my format with this. I started making it for fun to go through as many of Zoe's events and only halfway through decided I could actually post my findings to benefit others if they were having troubles or doing runthroughs without wanting to spend too much time.

Requirements in Short mode
So far it appears Creativity, Charm, and Fun are the three stats she needs. Keeping track of several playthroughs I find the lowest requirements are as follows:
Hearts - 12+
Smarts = 7
Bold = 1
Creativity = 12 confirmed (could be 11)
Charm = 7 confirmed
Fun = 6 confirmed
Money = 1

Hearts and Smarts could be lower but I had a difficult time trying to lower my Smarts in game while making the base requirements to prove the necessary stats. My guess is Smarts does NOT matter.

Basic SOP - get Creativity and Fun high right away and you could wing it with most events for her.

Quiz answers for Zoe:
Zodiac sign = Now-cannon lovers
Naming children = Name of my favorite ship
Deal-breaker for potential lover = They think Asuka is the best waifu
Sexiest type of knowledge = Accurate approximation of all fictional character's genitalia
Genie in a bottle = Shinji and Kaworu
D&D Character = Fanfic Bard
Autobiography = When Garfield Met Naruto
Dream First Date = A fierce fight to start a lifelong rivalry open to something else
Product slogan = For fans by fans
Killer accessory = Sailor Moon's Magic Wand
Most appealing in a partner = TENTACLES
World is ending = Netflix and Chill
Anniversary gift = Picasso
Ice cream = Ikasumi
Stripper Stage Name = Kawaii ♥♥♥♥♥ uwu

Some of these answers play directly into event choices you may stumble across. Most often Zoe choices favor the Creativity stat for the 'best' or 'most canon' answers.

Lunch:
Vera feeding credit cards to her snakes - Allegiances, preferences, sentiments = Zoe
Vera and Zoe doing something suspicious - The prisoner is lonely = Zoe
Polly's existential lunchtime crisis - SECRET BACKSTORY = Zoe
Damien inspecting Zoe - Kissing mouth = Zoe
Damien's #1 mug - Psst, Zoe = Zoe
Calculester and Vending Machines - Obsessive Online Research = Zoe
Calculester and 'Fresh' Sanity - 5 worst things = Zoe
Scott and Sanity - Sanity is high in cholesteral! = Zoe
Scott and Pizza Sandwich - Searching for pizza in the wild = Zoe
Scott and Marshmallow challenge - We can't control how many mouths we have = Zoe
Liam and Kpop Burritos - Contemplating exisitential meaningless = Zoe
Liam and Coven - Secret, double-crossing, mid-season-reveal alliance/romance = Zoe
Miranda and her eating serfs - Only the most expensive and rare = Zoe
Miranda and Zoe EXTRA perky - French fries deserve french kisses = Zoe
Dahlia and Damien NOT fighting - Secret Sexy Feelings = Zoe

According to other guides lunch gives +3 hearts so it doesn't hurt to make sure to guarantee Zoe likes you.

Zoe versus other love interests:

Liam and Ninja Turtle HJs:
Dehumanizing female gaze = Smarts (Damien)
Yaoi is Gluten = Charm (Zoe)

Damien Losing His Horn:
Demon horns are aphrodisiacs = Charm (Zoe)
Should have seen the other guys = Bold (Damien)

Scott's Muscles Fanfic:
Gulper Shark = Smarts (Scott)
A muscle's perspective = Creative (Zoe)

The Fanfiction of Marmanda Vandebunt:
You need to destroy Marmanda, not Zoe! = Bold (Zoe)

Killing Machine and Abyssal Terror:
Shirtless Damien pictures = Creative (Zoe)

Zoe capturing Polly:
Secrets are sexy = Creative (Polly)
Bag of cocaine = Wealth (Zoe)

Trying not to give away too much from the encounter but hoping key words help people find these when they really want to know.

Zoe events:

Zoe and Juan:
Your mistreatment is outrageous! = Charm
Tons of pictures = Creative

Artists Zoe and cheap Leonard:
Kidneys = Bold
Indentured servant = Creative

Library studying and Dmitri:
Terrible Commute = Smarts

Zoe playing FoF:
REAL Gamer Girl = Creative
No wrong way to play video games = Smarts

Who Watches the Watchmen:
Gem of Garoto = Smarts
CalArts sorting hat = Creative

Interdimensional Prince and marriage.
Married 17 times = Bold
Trampoline! = Fun

The "Cult & I".
GROSSFIT! = Smarts
Mobile game = Fun

ConCon!.
Neoliberal system = Smarts
Naruto and Garfield = Fun

The Coven! Say the thing!
Yell cliched and heroic one-liners = Smarts
Lick his abs = Fun

Coach's Sugar-coated Father.
Hip new mascot = Creative

"Senoir Regular Samuria Frogs".
Air the same show from 30 years ago = Smart
Surfer skater dog = Creative

Picnic in the Realm of Despair:
Coffee, blueberries, nuts = Smarts
Foil Anti-Void Hat = Wealth

Zoe group project with Vera and Calculester:
Improve the only stats that matter = Smarts

I know of at least 2 secret endings with Zoe at the center; Cultist ending, and Friendship ending. Both give special secret ending pictures.

Cultists Secret Ending

Helping with math homework.
"We're sorry" goat = Charm
Sacrifice your prejudices = Creative

Cultist Grandmaster.
Best theme song = Creative

Night of NWTBMPBTJODP CTRATPOTTM!
Slumber Party!!! = Fun

Friendship ending
Unfortunately I accidentally stumbled through this one without even knowing it. Generally this cool little subplot is dealing with Zoe running into several characters each time and usually you and a love interest helping her to be comfortable as herself and help others to understand her new identity and accept her for who she is now. It's pretty cute.

Zoe's story is pretty fun, wondering what other secrets are out there. Leonard is like her personal nemesis. I hope this little guide helps. Thanks to everyone else who enjoys the game and supports it as well!