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The adult human skeleton is composed of 206 bones. At birth, there are approximately 270 bones, with the final adult count decreasing as a portion of these bones fuse during phases of skeletal growth and maturation.

Bone is a metabolically active connective tissue that provides structural support, facilitates movement, and protects vital organs.
It plays an important role in regulating mineral and acid-base balance homeostasis. It also provides the environment for hematopoiesis (blood cells production) within the bone marrow.
Bone is composed of an extracellular matrix and bone cells (osteocytes)[1]. Under the right conditions, bone tissue undergoes a process of mineralization, formed by collagen matrix and hardened by deposited calcium. Bone tissue (osseous tissue) differs greatly from other tissues in the body. Bone is hard and many of its functions depend on that characteristic hardness.[2]The skeleton is composed of around 80% cortical bone and 20% trabecular bone.[3]
Much of the cellular activity in a bone consists of removal and replacement at the same site, a process called remodelling. The remodelling process occurs throughout life and becomes dominant by the time that bone reaches its peak mass (typically by the early 20s). Remodelling continues throughout life so that most of the adult skeleton is replaced about every 10 years