Melatonin is a natural compound, specifically an indoleamine, produced by and found in different organisms including bacteria and eukaryotes. It was discovered by Aaron B. Lerner and colleagues in 1958 as a substance of the pineal gland from cows that could induce skin lightening in common frogs. It was subsequently discovered as a hormone released in the brain at night which controls the sleep–wake cycle in vertebrates.

In vertebrates, melatonin is involved in synchronizing circadian rhythms, including sleep–wake timing and blood pressure regulation, and in control of seasonal rhythmicity including reproduction, fattening, moulting and hibernation. Many of its effects are through activation of the melatonin receptors, while others are due to its role as an antioxidant. Its primary function is to defend against oxidative stress in plants and bacteria.

⣿⣿⣿⣿⣿⠟⣉⣤⣶⣾⣿⣿⣿⣿⣷⣶⣤⣉⠻⣿⣿⣿⣿⣿⣿
⣿⣿⣿⡟⣡⣾⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣷⡌⢻⣿⣿⣿⣿
⣿⣿⡟⢠⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⡄⢿⣿⣿⣿
⣿⣿⡇⣾⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣷⢸⣿⣿⣿
⣿⣿⡇⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿⢸⣿⣿⣿
⣿⣿⣇⢹⣿⡿⠋⠉⠻⣿⣿⣿⣿⣿⣿⡿⠟⠿⣿⣿⡇⣸⣿⣿⣿
⣿⣿⣿⡈⢿⣇⠀⠀⢀⣿⣿⡿⢿⣿⣿⣾⣿⣿⣾⡿⢁⣿⣿⣿⣿
⣿⠟⢿⣷⡘⣿⣿⣿⣿⣿⣧⣴⣤⣴⣿⣿⣿⣿⣿⢃⣾⡿⠻⣿⣿
⡏⡄⠸⠟⠃⠈⠛⠛⠿⣿⣿⣿⠿⠛⠛⠻⣿⡿⠁⠘⠿⠇⢀⢹⣿
⡅⣿⣄⠀⣰⣾⣿⣷⡄⠘⠟⣡⣶⣿⣿⣦⠈⠁⠰⠿⠃⣠⣿⢸⣿
⣷⡹⢿⡀⢿⣿⣿⣿⣿⠀⣴⣿⣿⡟⢁⡀⠀⢰⣤⣶⣾⣿⢃⣾⣿
⣿⣿⣦⣀⠸⣿⣿⡟⠃⠸⣿⣿⣿⡇⠘⣛⠂⠾⠿⢟⣋⣵⣿⣿⣿
⣿⣿⣿⣿⣧⡘⠿⣿⠰⣶⣍⣛⣛⣃⣼⣿⣿⣿⣿⣿⣿⣿⣿⣿⣿

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⬛⬛🔴🔴🔴🔴⬛🔴⬛⬛🔴⬛🔴🔴🔴🔴⬛⬛
⬛⬛⬛⬛⬛🔴⬛🔴⬛⬛🔴⬛⬛⬛⬛🔴⬛⬛
⬛⬛🔴🔴🔴🔴⬛⬛🔴🔴⬛⬛🔴🔴🔴🔴⬛⬛
⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛⬛

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