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This rod-shaped bacterium has the ability to produce high levels of urease, which hydrolyzes urea to ammonia (NH3), so makes the urine more alkaline. If left untreated, the increased alkalinity can lead to the formation of crystals of struvite, calcium carbonate, and/or apatite, which can result in kidney stones.P. mirabilis is generally susceptible to most antibiotics apart from tetracycline(Tinker) and nitrofurantoin(Nisght Stalker)