Magdalene

Unlocked a new character.

Cain

Unlocked a new character.

Judas

Unlocked a new character.

The Womb

Chapter 4 - The Womb unlocked.

The Harbingers

The horsemen are loose.

A Cube of Meat

Unlocked a new item.

The Book of Revelations

Unlocked a new item.

A Noose

Unlocked a new item.

The Nail

Unlocked a new item.

A Quarter

Unlocked a new item.

A Fetus in a Jar

Unlocked a new item.

A Small Rock

Unlocked a new item.

Monstro's Tooth

Unlocked a new item.

Lil' Chubby

Unlocked a new item.

Loki's Horns

Unlocked a new item.

Something From The Future

New boss in the basement!

Something Cute

New boss in the caves!

Something Sticky

New boss in the depths!

A Bag of Pennies

Unlocked a new item.

The Book of Sin

Unlocked a new item.

Little Gish

Unlocked a new item.

Little Steven

Unlocked a new item.

Little C.H.A.D.

Unlocked a new item.

A Gamekid

Unlocked a new item.

A Halo

Unlocked a new item.

Mr. Mega

Unlocked a new item.

The D6

Isaac now holds the D6!

The Scissors

Unlocked a new item.

The Parasite

Unlocked a new item.

???

Unlocked a new character.

Everything is Terrible!!!

The game just got harder!

It Lives!

Your future's past waits.

Mom's Contact

Unlocked a new item.

The Necronomicon

Unlocked a new item.

Basement Boy

Beat basement without taking damage.

Spelunker Boy

Beat caves without taking damage.

Dark Boy

Beat depths without taking damage.

Mama's Boy

Beat womb without taking damage.

Golden God!

You are the best!!

Eve

Unlocked a new character.

Mom's Knife

Unlocked a new item.

Guardian Angel

Unlocked a new item.

A Bag of Bombs

Unlocked a new item.

Demon Baby

Unlocked a new item.

The D20

Unlocked a new item.

Bloody Lust

Unlocked a new item.

Blood Penny

Unlocked a new item.

Blood Rights

Unlocked a new item.

The Polaroid

Unlocked a new item.

Dad's Key

Unlocked a new item.

Lucky Toe

Unlocked a new item.

Guppy's Hairball

Unlocked a new item.

A Forgotten Horseman

Unlocked a new boss!

Samson

Unlocked a new character.

Isaac's Head

Unlocked a new item.

Maggy's Faith

Unlocked a new item.

Judas' Tongue

Unlocked a new item.

Cain's Eye

Unlocked a new item.

The Left Hand

Unlocked a new item.

The Negative

Unlocked a new item.

Azazel

Unlocked a new character.

Lazarus

Unlocked a new character.

Eden

Unlocked a new character.

Dead Boy

Beat Chest or Dark Room without taking damage.

Lucky Rock

Destroy 100 rocks.

The Cellar

Alt stage to the basement.

The Catacombs

Alt stage to the caves.

The Necropolis

Alt stage to the depths.

Rune of Jera

Unlocked a new item.

Rune of Ansuz

Unlocked a new item.

Chaos Card

Unlocked a new item.

Isaac's Tears

Unlocked a new item.

???'s Only Friend

Unlocked a new item.

Broken Ankh

Unlocked a new item.

Pandora's Box

Unlocked a new item.

Satanic Bible

Unlocked a new item.

Daemon's Tail

Unlocked a new item.

Abaddon

Unlocked a new item.

Blue Map

Unlocked a new item.

There's Options

Unlocked a new item.

Black Candle

Unlocked a new item.

Wire Coat Hanger

Unlocked a new item.

Ipecac

Unlocked a new item.

Experimental Treatment

Unlocked a new item.

Krampus

Unlocked another miniboss!

Head of Krampus

Unlocked a new item.

Super Meat Boy

Built him out of meat cubes.

Butter Bean

Unlocked a new item.

Little Baggy

Unlocked a new item.

Blood Bag

Unlocked a new item.

The D4

Unlocked a new item.

Missing Poster

Unlocked a new item.

Rubber Cement

Unlocked a new item.

Store Upgrade lv.1

Donated 20 pennies to the shop.

Store Upgrade lv.2

Donated 100 pennies to the shop.

Store Upgrade lv.3

Donated 200 pennies to the shop.

Angels

They are waiting.

The Tank

Unlocked Challenge #5.

Solar System

Unlocked Challenge #6.

Suicide King

Unlocked Challenge #7.

Cat Got Your Tongue

Unlocked Challenge #8.

Demo Man

Unlocked Challenge #9.

Cursed!

Unlocked Challenge #10.

The Family Man

Unlocked Challenge #19.

Purist

Unlocked Challenge #20.

Lost Baby

Unlocked a new co-player baby.

Cute Baby

Unlocked a new co-player baby.

Shadow Baby

Unlocked a new co-player baby.

Glass Baby

Unlocked a new co-player baby.

Wrapped Baby

Unlocked a new co-player baby.

Begotten Baby

Unlocked a new co-player baby.

Glitch Baby

Unlocked a new co-player baby.

Fighting Baby

Unlocked a new co-player baby.

Lord of the Flies

You became Lord of the Flies.

Fart Baby

Unlocked a new item.

Maw of the Void

Unlocked a new item.

Lil' Chest

Unlocked a new item.

My Shadow

Unlocked a new item.

Cracked Dice

Unlocked a new item.

Lilith

Unlocked a new character.

Key Bum

Unlocked a new item.

Box of Friends

Unlocked a new item.

Serpent's Kiss

Unlocked a new item.

Blue Womb

Unlocked a hidden chapter.

Lucky Pennies

Unlocked a new item.

Wooden Nickel

Unlocked a new item.

Cain holds Paperclip

Unlocked a new starting item.

XXXXXXXXL

Unlocked Challenge #21.

SPEED!

Unlocked Challenge #22.

Blue Bomber

Unlocked Challenge #23.

PAY TO PLAY

Unlocked Challenge #24.

Have a heart

Unlocked Challenge #25.

I RULE!

Unlocked Challenge #26.

BRAINS!

Unlocked Challenge #27.

PRIDE DAY!

Unlocked Challenge #28.

Onan's Streak

Unlocked Challenge #29.

The Guardian

Unlocked Challenge #30.

Cry Baby

Unlocked a new co-player baby.

Red Baby

Unlocked a new co-player baby.

Green Baby

Unlocked a new co-player baby.

Black Baby

Unlocked a new co-player baby.

Goat Head Baby

Unlocked a new co-player baby.

Special Hanging Shopkeepers

Unlocked a secret.

Everything is Terrible 2!!!

Greed just got harder!

Backasswards

Unlocked a new challenge.

Aprils fool

Unlocked a new challenge.

Pokey Mans

Unlocked a new challenge.

Ultra Hard

Unlocked a new challenge.

PONG

Unlocked a new challenge.

Silver Dollar

Unlocked a new item.

Dark Prince's Crown

Unlocked a new item.

Compound Fracture

Unlocked a new item.

New Area

Unlocked a new area.

Once More with Feeling!

Unlocked a new item.

Sin collector

Unlocked a new item.

ZIP!

Unlocked a new item.

Mr. Resetter!

Unlocked a new item.

Living on the edge

Unlocked a new item.

U Broke It!

Unlocked a new item.

Delirious

Unlocked a new item.

Apollyon

Unlocked a new character.

Burning Basement

Alt stage to the basement.

Flooded Caves

Alt stage to the caves.

Dank Depths

Alt stage to the depths.

Scarred Womb

Alt stage to the womb.

Something wicked this way comes!

Unlocked new bosses!

The gate is open!

Unlocked new enemies!

Mystery Gift

Unlocked a new item.

Sprinkler

Unlocked a new item.

Angry Fly

Unlocked a new item.

Bozo

Unlocked a new item.

Buddy in a Box

Unlocked a new item.

Fast Bombs

Unlocked a new item.

Lil Delirium

Unlocked a new item.

Hairpin

Unlocked a new item.

Wooden Cross

Unlocked a new item.

Butter

Unlocked a new item.

Ancient Recall

Unlocked a new item.

Era Walk

Unlocked a new item.

Coupon

Unlocked a new item.

Telekinesis

Unlocked a new item.

Jumper Cables

Unlocked a new item.

Leprosy

Unlocked a new item.

Technology Zero

Unlocked a new item.

Filigree Feather

Unlocked a new item.

Mr. Me

Unlocked a new item.

7 Seals

Unlocked a new item.

Angelic Prism

Unlocked a new item.

Pop!

Unlocked a new item.

Door Stop

Unlocked a new item.

Death's List

Unlocked a new item.

Haemolacria

Unlocked a new item.

Lachryphagy

Unlocked a new item.

Schoolbag

Unlocked a new item.

Trisagion

Unlocked a new item.

Extension Cord

Unlocked a new item.

Sacrificial Altar

Unlocked a new item.

Lil Spewer

Unlocked a new item.

Rotten Penny

Unlocked a new item.

Baby-Bender

Unlocked a new item.

Flat Stone

Unlocked a new item.

Mystery Egg

Unlocked a new item.

Jacob and Esau

You are just like your father...

The Planetarium

Kids shouldn't believe in fortunes...

A Secret Exit

Complete ??? 3 times.

Rotten Heart

Enter the Corpse...

Dross

Defeat all bosses in Downpour.

Gehenna

Defeat all bosses in the Mausoleum.

Red Key

The other side is calling...

Candy Heart

Complete the final chapter with Magdalene.

Devil's Crown

Complete the Corpse with Azazel.

Lil Abaddon

Complete the final chapter with Azazel.

The Broken

???

The Dauntless

???

The Benighted

???

Isaac's Awakening

Unlocked a new challenge.

Seeing Double

Unlocked a new challenge.

Brimstone Bombs

Kill Hornfel before he escapes!

Member Card

Spend 40+ pennies in a single shop.

Golden Razor

Obtain 99 pennies. Then spend every single one of them.

A Strange Door

Where could it lead to?

Something Icky

New boss in the womb!

Purity

Unlocked a new item.

D12

Unlocked a new item.

Betrayal

Unlocked a new item.

Fate's Reward

Unlocked a new item

Athame

Unlocked a new item.

Blind Rage

Unlocked a new item.

Empty Vessel

Unlocked a new item.

Eden's Blessing

Unlocked a new item.

Sworn Protector

Unlocked a new item.

Incubus

Unlocked a new item.

Censer

Unlocked a new item.

Evil Eye

Unlocked a new item.

Black Feather

Unlocked a new item.

Lusty Blood

Unlocked a new item.

GB Bug

Unlocked a new item.

Zodiac

Unlocked a new item.

Rune Bag

Unlocked a new item.

Cambion Conception

Unlocked a new item.

Succubus

Unlocked a new item.

Immaculate Conception

Unlocked a new item.

Gold Heart

Unlocked a new item.

Get out of Jail Free Card

Unlocked a new item.

Gold Bomb

Unlocked a new item.

2 new pills

Unlocked a new item.

2 new pills

Unlocked a new item.

Poker Chip

Unlocked a new item.

Stud Finder

Unlocked a new item.

D8

Unlocked a new item.

Kidney Stone

Unlocked a new item.

Blank Rune

Unlocked a new item.

Brown Baby

Unlocked a new co-player baby.

Blue Baby

Unlocked a new co-player baby.

Lil' Baby

Unlocked a new co-player baby.

Rage Baby

Unlocked a new co-player baby.

Long Baby

Unlocked a new co-player baby.

Yellow Baby

Unlocked a new co-player baby.

White Baby

Unlocked a new co-player baby.

Big Baby

Unlocked a new co-player baby.

Hive Baby

Unlocked a new co-player baby.

Buddy Baby

Unlocked a new co-player baby.

Colorful Baby

Unlocked a new co-player baby.

Whore Baby

Unlocked a new co-player baby.

Cracked Baby

Unlocked a new co-player baby.

Dripping Baby

Unlocked a new co-player baby.

Blinding Baby

Unlocked a new co-player baby.

Sucky Baby

Unlocked a new co-player baby.

Dark Baby

Unlocked a new co-player baby.

Picky Baby

Unlocked a new co-player baby.

Revenge Baby

Unlocked a new co-player baby.

Belial Baby

Unlocked a new co-player baby.

Special Shopkeepers

Unlocked a secret.

Eve now holds Razor Blade

Unlocked a new starting item.

Store Key

Unlocked a new item.

Lost holds Holy Mantle

Unlocked a new starting item.

Mega

Unlocked...

Keeper now holds... A Penny!

Unlocked a new item.

Rib of Greed

Unlocked a new item.

Noose Baby

Unlocked a new item.

1001%

Nerd x 1000000

Keeper holds Wooden Nickel

Unlocked a new starting item.

Keeper holds Store Key

Unlocked a new starting item.

Deep Pockets

Unlocked a new item.

Karma

Unlocked a new item.

Sticky Nickels

Unlocked a new item.

Super Greed Baby

Unlocked a new item.

Keeper

Unlocked a new character.

Sale Baby

Unlocked a new item.

D Infinity

Unlocked a new item.

Eucharist

Unlocked a new item.

Shade

Unlocked a new item.

King Baby

Unlocked a new co-player baby.

Bloody Crown

Unlocked a new item.

Dull Razor

Unlocked a new item.

Eden's Soul

Unlocked a new item.

Euthanasia

Unlocked a new item.

Holy Card

Unlocked a new item.

Crooked Penny

Unlocked a new item.

Void

Unlocked a new item.

D1

Unlocked a new item.

Glyph of Balance

Unlocked a new item.

Sack of Sacks

Unlocked a new item.

Eye of Belial

Unlocked a new item.

Meconium

Unlocked a new item.

Stem Cell

Unlocked a new item.

Crow Heart

Unlocked a new item.

Metronome

Unlocked a new item.

Bat Wing

Unlocked a new item.

Plan C

Unlocked a new item.

Duality

Unlocked a new item.

Dad's Lost Coin

Unlocked a new item.

Eye of Greed

Unlocked a new item.

Black Rune

Unlocked a new item.

Locust of Wrath

Unlocked a new item.

Locust of Pestilence

Unlocked a new item.

Locust of Famine

Unlocked a new item.

Locust of Death

Unlocked a new item.

Locust of Conquest

Unlocked a new item.

Hushy

Unlocked a new item.

Brown Nugget

Unlocked a new item.

Mort Baby

Unlocked a new co-player baby.

Smelter

Unlocked a new item.

Apollyon Baby

Unlocked a new co-player baby.

Hat trick!

Unlocked a new item.

5 Nights at Mom's

Unlocked super special rocks.

Dedication

Unlocked a new item.

It's the Key

Unlocked a new item.

Laz Bleeds More!

Unlocked a new starting item.

Maggy Now Holds a Pill!

Unlocked a new starting item.

Charged Key

Unlocked a new item.

Samson Feels Healthy!

Unlocked a new starting item.

Greed's Gullet

Unlocked a new item.

The Marathon

Unlocked a new item.

RERUN

Unlocked the power of RERUN.

Greedier!

New mode unlocked!

Something wicked this way comes+!

Unlocked even more bosses!

Black Hole

Unlocked a new item.

Broken Modem

Unlocked a new item.

Huge Growth

Unlocked a new item.

Moving Box

Unlocked a new item.

Blanket

Unlocked a new item.

Marbles

Unlocked a new item.

Bethany

Beat Hard mode as Lazarus without losing a life

Forgotten Lullaby

Get that song out of her head.

Fruity Plum

Defeat Baby Plum 10 times.

Plum Flute

Make a new friend!

Ashpit

Defeat all bosses in the Mines.

Wisp Baby

Beat the game in Hard mode with Bethany.

Book of Virtues

Complete the Cathedral with Bethany.

Urn of Souls

Complete Sheol with Bethany.

Blessed Penny

Complete the Chest with Bethany.

Alabaster Box

Complete the Dark Room with Bethany.

Beth's Faith

Complete Boss Rush with Bethany.

Soul Locket

Beat Greed mode with Bethany.

Divine Intervention

Complete ??? with Bethany.

Vade Retro

Beat Greedier mode with Bethany.

Star of Bethlehem

Beat the Void with Bethany.

Hope Baby

Beat everything in Hard mode with Bethany.

Glowing Baby

Defeat Mega Satan with Bethany.

Double Baby

Beat the game in Hard mode with Jacob and Esau.

The Stairway

Complete the Cathedral with Jacob and Esau.

Red Stew

Complete Sheol with Jacob and Esau.

Birthright

Complete the Chest with Jacob and Esau.

Damocles

Complete the Dark Room with Jacob and Esau.

Rock Bottom

Complete Boss Rush with Jacob and Esau.

Inner Child

Beat Greed mode with Jacob and Esau.

Vanishing Twin

Complete ??? with Jacob and Esau.

Genesis

Beat Greedier mode with Jacob and Esau.

Suplex!

Complete the Void with Jacob and Esau.

Solomon's Baby

Beat everything in Hard mode with Jacob and Esau.

Illusion Baby

Defeat Mega Satan with Jacob and Esau.

Meat Cleaver

Complete the Corpse with Isaac.

Options?

Complete the final chapter with Isaac.

Yuck Heart

Complete the Corpse with Magdalene.

Guppy's Eye

Complete the Corpse with Cain.

A Pound of Flesh

Complete the final chapter with Cain.

Akeldama

Complete the Corpse with Judas.

Redemption

Complete the final chapter with Judas.

Eternal D6

Complete the Corpse with ???.

Montezuma's Revenge

Complete the final chapter with ???.

Bird Cage

Complete the Corpse with Eve.

Cracked Orb

Complete the final chapter with Eve.

Bloody Gust

Complete the Corpse with Samson.

Empty Heart

Complete the final chapter with Samson.

Tinytoma

Complete the Corpse with Lazarus.

Astral Projection

Complete the final chapter with Lazarus.

'M

Complete the Corpse with Eden.

Everything Jar

Complete the final chapter with Eden.

Lost Soul

Complete the Corpse with the Lost.

Hungry Soul

Complete the final chapter with the Lost.

Blood Puppy

Complete the Corpse with Lilith.

C Section

Complete the final chapter with Lilith.

Keeper's Sack

Complete the Corpse with Keeper.

Keeper's Box

Complete the final chapter with Keeper.

Lil Portal

Complete the Corpse with Apollyon.

Worm Friend

Complete the final chapter with Apollyon.

Bone Spurs

Complete the Corpse with the Forgotten.

Spirit Shackles

Complete the final chapter with the Forgotten.

Revelation

Complete the Corpse with Bethany.

Jar of Wisps

Complete the final chapter with Bethany.

Magic Skin

Complete the Corpse with Jacob and Esau.

Friend Finder

Complete the final chapter with Jacob and Esau.

Bloody Mary

Unlocked a new challenge.

Baptism by Fire

Unlocked a new challenge.

Pica Run

Unlocked a new challenge.

Hot Potato

Unlocked a new challenge.

Cantripped!

Unlocked a new challenge.

Red Redemption

Unlocked a new challenge.

Charged Penny

They will charge you up... for a small fee.

Old Capacitor

Kill 10 Battery Bums.

Mega Mush

Beat everything in Hard Mode as every character.

Dead God

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