In 1939 it set a world's closed circuit distance record when it covered 10,000 km at an average speed of 239.67 km/h, remaining in the air for 56.5 hours. The aircraft saw extensive service throughout all the various African campaigns.

The SM.82 was developed from the earlier SM.75 Marsupiale civil transport as a heavy bomber and military transport. Although having the same configuration of the SM.75, the SM.82 was larger. The aircraft was quickly developed and the prototype first flew in 1939. Although underpowered and slow, it was capable of carrying heavy loads, including the L3 light tank and a complete disassembled CR.42 fighter (these loads demanded special modifications). It had both cargo and troop transport capability, with room for up to 40 men and their equipment.

Deliveries to the Regia Aeronautica began in 1940. However, production rates were slow, with only 100 aircraft delivered in 1940, and another 100 in 1941, so that there were never enough of these aircraft in service. By 1942 production doubled to 200 a year, while in 1944 almost 300 were produced, by which time the factory was under the control of the Germans.

The Savoia-Marchetti SM.82 Marsupiale is an Italian bomber and transport aircraft of World War II. It was a cantilever, mid-wing monoplane trimotor with a retractable, tailwheel undercarriage. There were 875 (plus one prototype) built, the first entering service in 1940. Although able to operate as a bomber with a maximum bombload of up to 8,818 lb (4000 kg), the SM.82 saw very limited use in this role. The SM.82 was the foreign aircraft used in largest number by the Luftwaffe, which operated several hundreds of this aircraft, as a transport. Post-war about 30 SM.82s continued in service with the Aeronautica Militare Italiana, many remaining in service until the early 1960s.