Doesn't need any configuration, default settings of rpcs3 are the reccomended, just change it to Vulkan and select your resolution and you are good.

There are some kinda of shader or bloom issue on the face of some characters (Ayane, Murai, Rachel) and shadow disappears sometimes too.

Issues:
#1) All movies plays at frame to frame with audio.

#2) There are slowdowns here and there for old cpus but most of the time it runs 60 or 45+ fps, modern cpu like i7 6700 or later and Ryzen 1500X and above are likely to play this game 60fps most of the time with few drops if any.

Screenshots 4k downsampled to 1080p compressed to .jpg: https://imgur.com/a/vsGGN

rpcs3-v0.0.5-6639-90e0bade_win64 and later builds have fixed the rare random crash.

Ryzen 5 1500X and above or I7 6700 at 3.8GHz and above are reccomended to run 60fps all/most of time.

Any GPU that supports Vulkan can run it at 4k. (if you have a gtx960 or better you are good)

more info here:
https://steamproxy.net/groups/bringninjagaidensigmaforpc/discussions/0/1696044439569628463/