Everything planned for the guide at the moment is listed below.
As of right now, I am giving this guide a lot less attention since everything I primarily wanted to be finished, is finished. If you have made a guide for an unfinished topic that I've listed below, I would be happy to link it here to redirect people to your work. If you want to contribute to this guide, I'm more than happy to include your information as well to further increase it's usefulness.

Main Topics

[✓] Getting Started
[✓] Related Achievements
[✓] Floor Hidden Passages
[✓] Important Floor Loot
[✓] Exisals
[✓] Bosses
[✓] Unique Items

Low Priority Topics

[_] Enemies (20%)
[_] Character Skill Effects (0%)

Topics I won't be adding

[_] Party Compositions / Meta Teams

Whenever a topic is marked with a ✓, that means it is a fully complete topic. It may be subject to edit even after being marked finished if there any errors or missing information. More topics may be added to this list later.

I'll respond to any questions you have in the comments.

If you're having trouble getting through the Despair Dungeon, this guide should be able to help you. There's a couple of important things to note before you start your journey into the Despair Dungeon. First things first:

Despair Dungeon requires concrete solutions, but it can take a few different forms. For these exact solutions read on below.

Read the underlined passages if TL:DR

• Influence: Maximum hit points.
  
• Focus: Maximum skill points.
  
• Strength: Increase in normal attack power & physical skill power. Such as the skill "Sword Stab"
  
• Defense: Increase in normal attack & physical skill damage reduction
  
• Intellect: Increase in intelligence skill power. Such as the skill "Electric Paralyze"
  
• Fortitude: Increase in intelligence skill damage reduction & negative status resist.
  
• Agility: Determines turn order as well as dodge chance.
  
• Luck: Determines run away chance as well as crit chance.

Note: Party member with highest luck determines run away chance.
Note: Stats can increase above 999. The cap is only visual.

• You can press X or ESC to sprint in the dungeon.
  
  
• You should raise 4 individual party members through the Talent Development Plan. Having a full party is important to being successful in the dungeon.
  
  
• These 4 members should be diverse in some ways. I recommend getting at least one of each character type. 1 sport type, 1 intelligence type, and 1 variety type character. The 4th member's type is up to you.
  
  
• Characters you develop cannot be leveled up more after graduating the Talent Development Plan. Use your 3 years wisely to make the most of your future dungeon crawling ultimates. You can however change their development, by putting that same character's death card through the development plan again. You will simply overwrite the previous result.
  
  
• I won't go into too much leveling detail in this guide, but having a character who can use Sports Physical skills and a character who can use Intelligence Magical skills effectively is important. Enemies can be resistant to certain types of damage.
  
  
• Variety characters are important, because they generally have higher defense stats. This makes them generally worse at combat, but good at surviving and being able to cast variety type skills safely. Variety type skills include a Heal, Status Cure, and Resurrect.
  
  
• Any character can have any skills, but it's important to assign general roles based on stats. Sport types accel at strength, Intelligence types accel at intellect, Variety types accel in defense and fortitude. Each one of these attributes has an item to increase it, so you can assign roles based on them.
  
  
• Following that any character can have any skills, you may want to establish the Fighting Spirit skill on 2 characters, in case one of the characters with that skill is knocked out. In addition, you should consider giving Absorb Focus to any character, as it is the only way to restore focus besides leaving the dungeon.
  
  
• Try to give characters decent skill variety instead of high level skills, unless you want them to be a one trick kind of character. Low level skills can be useful, such as fighting spirit. S & U tier characters have an easier time getting higher level skills while maintaining diversity, and level 10 skills usually have an extra effect (Such as fighting spirit affecting the whole party). So use your best judgement.
  
  
• It is recommended you swap out any normal tier characters for S tier characters you may get from the Death Cards machine as they come. S tier and U tier characters have better progression while leveling.
  
  
• There is a boss every 10 levels, and an elevator every 5 levels. Make sure to use the elevators to restore your character's Influence and Focus, and save your progress. You can travel to the floors with elevators at any time from the base as long as you have activated them.
  
  
• Your chances at higher tier characters increase when you reach the floor after a boss, so say you beat the boss on floor 10, you should go to floor 11 before using the death cards machine for a better chance at S tier characters.
  
  
• Any chests opened and bosses defeated will be saved, even if your party is wiped out in the Despair Dungeon.

The multiplier applied to gained talent points and levels.

• Normal Tier: 1x Multiplier (AVG Lvl: 15)
  
• S Tier: 2x Multiplier (AVG Lvl: 45)
  
• U tier: 5x Multiplier (AVG Lvl: 99)

The First of Many

Defeat the boss on floor 10 of the Despair Dungeon.



Reaching the Summit

Defeat the boss on floor 50 of the Despair Dungeon.



Overcoming True Fear

Defeat the hidden boss on floor 100 of the Despair Dungeon.



It should be noted that clearing floors 51-100 will most likely require you to have U tier characters, or have farmed gear, as the difficulty becomes much harder. Some situtations may require you to specifically develop characters for the completion of tasks, such as a skill needed to protect yourself from a boss attack.

Upon reaching the 100th floor and slaying the boss, the game credits will roll as they did after the 50th's floors boss. However you will get a message asking you afterwards "Clear save data?" in addition to a message that a hidden boss has appeared on the 100th floor. Say "Yes" to the prompt to clear your save data after defeating the floor 100 boss and you will be able to progress through floor 100 normally from there upon continuing your game. An elevator will be in the back of the floor, as well as the true final boss of the Despair Dungeon.

The hidden boss isn't difficult, but requires specific preparation. A further look into this boss and the rest can be found later in the guide.

Chests:

Item Chest





Rare Material Chest





Death Card Ticket Chest





Gold Chest

Item Chests (Not Including Exisal Chests)

• Floor 4 : Top left corner. (Tattered Uniform)
  
• Floor 5 : Bottom right area. (Cheap Shoes)
  
• Floor 6 : Bottom left corner. (Cheap Talisman)
  
• Floor 8 : Bottom right area. (Cheap hat)
  
• Floor 10 : After boss. (Staff 2)
  
• Floor 12 : Bottom left area. (Regular Talisman)
  
• Floor 13 : At the end of a long path. (Regular Uniform)
  
• Floor 15 : In the upper center part of the map. (Hacking Gun 2)
  
• Floor 17 : Upper left part of the map. (Regular Hat)
  
• Floor 19 : Left side of the map. (Shield Dash)
  
• Floor 20 : After boss. (Staff Dash)
  
• Floor 22 : Upper right corner. (Regular Hat)
  
• Floor 22 : Center left of the area. (Regular Talisman)
  
• Floor 22 : Bottom left of the area. (Regular Shoes)
  
• Floor 22 : Bottom right corner. (Regular Uniform)
  
• Floor 25 : In the upper center of the area. (Hacking Gun Dash)
  
• Floor 28 : In the center right area. (Intellectual Shoes)
  
• Floor 28 : In the left area. (Intellectual Hat)
  
• Floor 29 : Bottom left corner. (Intellectual Uniform)
  
• Floor 30 : After the boss. (Super Katana)
  
• Floor 30 : After the boss. (Super Staff)
  
• Floor 34 : Bottom left corner. (Safety Talisman)
  
• Floor 36 : Top center at the end of a walkway. (Ultra Shield)
  
• Floor 37 : Center right isolated square area. (Hard Worker's Shoes)
  
• Floor 39 : Top left corner. (Hard Worker's Uniform)
  
• Floor 40 : After the boss. (High Speed Katana)
  
• Floor 40 : After the boss. (High Speed Gun)
  
• Floor 47 : Top left area. (Ultimate Hat)
  
• Floor 48 : In a classroom. (Ultimate Talisman)
  
• Floor 50 : After the boss. (Ultimate Uniform)
  
• Floor 54 : Top left corner. (Uniform of Courage
  
• Floor 55 : Bottom right area. (Shoes of Courage)
  
• Floor 56 : Bottom left corner. (Talisman of Courage)
  
• Floor 58 : Bottom right area. (Hat of Courage)
  
• Floor 60 : After the boss. (Hacking Gun 3)
  
• Floor 62 : Bottom left corner. (Talisman of Victory)
  
• Floor 63 : At the end of a walkway. (Uniform of Victory)
  
• Floor 65 : Center middle area. (Katana 3)
  
• Floor 67 : Top left corner. (Hat of Magic)
  
• Floor 69 : Left side of the area. (Shield Impact)
  
• Floor 70 : After the boss. (Staff Impact)
  
• Floor 75 : Center area. (Katana Impact)
  
• Floor 79 : Bottom left area. (Uniform of Magic)
  
• Floor 80 : After the boss. (Champion's Uniform)
  
• Floor 80 : After the boss. (Champion's Talisman)

Rare Material Chests

• Floor 72 : Top right corner. (Gold Skin)
  
• Floor 72 : Top left area. (Gold Eye)
  
• Floor 72 : Bottom left area. (Gold Meat)
  
• Floor 72 : Bottom right corner. (Gold Fur)

Ticket Chests

• Floor 14 : Hidden Passage Chest. (S Ticket)
  
• Floor 24 : Hidden Passage Chest. (S Ticket)
  
• Floor 27 : At the end of the long spiral walk. (S Ticket)
  
• Floor 30 : After the boss. (S Ticket)
  
• Floor 33 : Hidden Passage Chest. (S Ticket)
  
• Floor 40 : After the boss. (S Ticket x2)
  
• Floor 42 : Bottom left side. (S Ticket)
  
• Floor 43 : Top right corner. (S Ticket)
  
• Floor 45 : Center right area block. (S Ticket)
  
• Floor 46 : Top right corner. (S Ticket)
  
• Floor 47 : Hidden Passage Chest. (S Ticket x2)
  
• Floor 49 : After each boss. (S Ticket x4)
  
• Floor 50 : After the boss. (U Ticket x2)
  
• Floor 64 : Hidden Passage Chest. (U Ticket)
  
• Floor 74 : Hidden Passage Chest. (U Ticket)
  
• Floor 77 : At the end of the long spiral walk. (U Ticket)
  
• Floor 80 : After the boss. (U Ticket)
  
• Floor 83 : Hidden Passage Chest. (U Ticket)
  
• Floor 86 : Top center area. (U Ticket)
  
• Floor 87 : Center right isolated square area. (U Ticket)
  
• Floor 89 : Top left corner. (U Ticket)
  
• Floor 90 : After the boss. (U Ticket x2)
  
• Floor 92 : Bottom left area. (U Ticket)
  
• Floor 93 : Top right area. (U Ticket)
  
• Floor 95 : In the center. (U Ticket)
  
• Floor 96 : Top right area. (U Ticket)
  
• Floor 97 : Bottom right area. (U Ticket x2)
  
• Floor 99 : After each boss. (U Ticket x4)

Hidden Passages

Hidden passages are walls you can walk through to find hidden treasure.




Floor 14 has a hidden passageway at this spot on the map.







Floor 24 has a hidden passageway at this spot on the map.







Floor 33 has a hidden passageway at this spot on the map.







Floor 47 has a hidden passageway at this spot on the map.







Floor 64 has a hidden passageway at this spot on the map.







Floor 74 has a hidden passageway at this spot on the map.







Floor 83 has a hidden passage way at this spot on the map.
It has turns, so you'll need to blindly navigate a bit.






Floor 97 has a hidden passageway here, but it only hides gold chests.

Exisal Blue: Floor 25
Skill(s): Zeal, Sword Stab
Hitpoints: 5000
Resistances: Status effects
Treasure: Ultimate Pianist Proof, Ultimate Astronaut Proof, Ultimate ??? Proof, Ultimate Supreme Leader Proof, Ultimate Robot Proof, Ultimate Child Caregiver Proof, Ultimate Aikido Master Proof, Ultimate Cosplayer Proof, 10000G.

Exisal Yellow: Floor 45
Skill(s): Zeal, Electric Paralyze
Hitpoints: 5000
Resistances: Status effects
Treasure: Ultimate Magician Proof, Ultimate Maid Proof, Ultimate Detective Proof, Ultimate Tennis Pro Proof, Ultimate Inventor Proof, Ultimate Artist Proof, Ultimate Entomologist Proof, Ultimate Anthropologist Proof. 20000G.


Exisal Green: Floor 48
Skill(s): Zeal, Electric Paralyze, Sword Stab
Hitpoints: 5000
Resistances: Status effects
Treasure: Ultimate Assassin Proof, Ultimate Survivor Proof, 40000G




Exisal Pink: Floor 75
Skill(s): Zeal, Electric Paralyze, Cure Condition, Sword Stab
Hitpoints: 99999
Resistances: All damage
Weakness: Poison
Treasure: U Ticket x2, Gold Eye x3, Gold Meat x3, Gold Fang x4, Gold Fur x3, Gold Skin x3, 99999G x2


Exisal Red: Floor 95
Skill(s): Zeal, Electric Paralyze, Sword Stab
Hitpoints: 55555(?)
Resistances: Status effects
Treasure: Platinum Meat, Platinum Fang, Platinum Eye, Platinum Skin, Platinum Fur, U Ticket x2, Ultimate Hope Proof, 99999G.



Exisal V3: Floor 98
Skill(s): Zeal, Electric Paralyze, Sword Stab
Hitpoints: 33333(?)
Resistances: Status effects
Treasure: Talisman of Legend, Shoes of Legend, Uniform of Legend, Hat of Legend, 99999G x2

All bosses before floor 51 can be poisoned. A high level poison can help immensely when trying to beat them. Note: Barrier skills are useful for preventing mass damage to your team from boss elemental skills.

Hitpoints: 800
Skills: Ice Freeze All
Resistance: Status
Reward: Staff 2
Floor 49 Reward: S Ticket & Gold
Weakness: Ice barrier, poison


Hitpoints: 1000
Skills: Wind Jet All
Resistance: Physical Damage, Status
Reward: Staff Dash
Floor 49 Reward: S Ticket & Gold
Weakness: Wind barrier, poison, elemental damage


Hitpoints: 1300
Skills: Summer Rain Fist, Zeal
Resistance: Status
Reward: Super Katana, Super Staff, S Ticket
Floor 49 Reward: S Ticket & Gold
Weakness: High agility stat for dodges / high defense
Note: Zeal cannot be debuffed

Hitpoints: 2000
Skills: Blind, All Down, Electric Paralyze All
Resistance: Status
Reward: S Ticket x2, High Speed Katana, High Speed Gun, Wind Jet
Floor 49 Reward: S Ticket & Gold
Weakness: Cure conditions, electric barrier, poison


Boss Rush! Progress is saved. You can bring multiple parties to clear.


Hitpoints: 7500
Skills: Falcon Kick, All Up, Ice Freeze All
Resistance: Status
Weakness: Debuff, Poison, Ice barrier, high agility




Hitpoints: 8000
Skill: Ice Freeze All, Poison All, Falcon Kick
Resistance: Status
Weakness: Ice barrier, cure status ailments




Hitpoints: 10000
Skills: Wind Jet All, Sleep All
Resistance: Physical Damage, Status
Weakness: Wind barrier, cure status ailments, high fortitude to resist sleep, elemental damage



Hitpoints: 13000
Skills: Summer Rain Fist, Zeal
Resistance: Status
Weakness: High agility stat to dodge his attacks
Note: Zeal cannot be debuffed



Hitpoints: 20000
Skills: Blind, All Down, Electric Paralyze All, Wind Jet
Resistance: Status
Weakness: Cure conditions, eletric barrier




Boss Rush! Progress is saved. You can bring multiple parties to clear.

Hitpoints: 40000
Skills: Falcon Kick, All Up, Ice Freeze All, Debuff
Resistance: Status
Weakness: Debuff, high agility, ice barrier




Hitpoints: 66666
Skills: Wind Jet All, Confuse, Despair, Summer Rain Fist.
Resistance: Status
Treasure: Ultimate Lucky Student Proof, 500000G.


Monokuma V3 will always crit on normal attacks. The boss will also usually do enough damage to instantly kill most party members with any attack, including his area of effect attacks. Wind Jet All can be negated with the Wind Barrier skill. Summer Rain Fist can be dodged with a high enough agility score. Confuse can be resisted by party members with a high fortitude level. A variety character with a staff and recover influence / cure condition skills will be necessary here. Despair can also be resisted by high fortitude, but does not have as much a serious effect as confuse. If a party member gets confused, they lose their turns and attack allies indefinitely until cured, and you can only control characters who are not affected by confuse. Despair makes your party members unable to recover HP.

If you want to see where you can find a monster/material from a specific monster, you can right click an item in the create menu to see the floors it appears on.

Copper, Silver, Gold, and Platinum Monokumamels do not show where they appear. It's believed the appropriate floors for those are listed below. The floors where they appear the most, are the floors right before switching to the next rarity.

Copper Monokumamel: (Floors 14, 19, 24, 29)
HP: 3
Gold Drop: 1000
Agility: ?

Silver Monokumamel: (Floors 34, 39, 44, 49)
HP: 4
Gold Drop: 2500
Agility: ?

Gold Monokumamel: (Floors 54, 59, 64, 69, 74, 79)
HP: 5
Gold Drop: 5000
Agility: ?

Platinum Monokumamel: (Floors 84, 89, 94, 99)
HP: 6
Gold Drop: 10000
Agility: ?

These rare Monokumamels will usually run away if not killed fast, so they must be focused down in an encounter if you want to get their materials and gold. Multi-hitting attacks work wonders for them, such as Falcon Kick.

Planning out this section.
Ther are only these types of enemies, but they get stronger as you go deeper into the dungeon.
Monokumamels: Basic enemy
Monodragon Head: Uses Mujin Cut ability
Curse Monogirl: Gives negative status effects, magic resistance
Fluffy Monobunny: Dodges attacks easily, resists Ice
Monokumantala: Dodges attacks easily
Monokuma Hermit: High Magic Resist
Monokuma Gather: High Physical Resist, use sacrifice
Floor Monodragon: Preforms multi-target magic attacks
Twisty Monokuma: High Magic Resist, can dodge attacks, absorb focus

These unique equipment pieces are gotten by defeating exisals, and one is obtained by defeating the hidden boss.

Google doc link here for all of them: Click here[docs.google.com]
Contributed by: Alicia

These weapons are tedious to create, as they require rare enemy materials. If you'd like to contribute the effect of any of these weapons in the comments, I will include it in the guide and include your name if you wish.

None of these weapons are required to beat the Despair Dungeon, but if you'd like to know what the weapons do, then they might be posted here.

Contributors: Drazoth, Nuckrieg, Despair Dungeon